• mschmidt-headshot-from-linkedin

    Mathias Schmidt, Ph.D.

    Chief Executive Officer

    Dr. Schmidt joined ArmaGen as the chief executive officer, as well as member of ArmaGen’s board of directors, in October 2016. Dr. Schmidt has more than 17 years of global biopharmaceutical industry experience in executive management focused on the research and development of biotherapeutics and pharmaceuticals. Prior to ArmaGen, he held various positions with Takeda Pharmaceuticals and its subsidiaries since 2001, including oncology drug discovery, early alliance management and overseeing biologics. He joined Takeda California in 2012 as Vice President of Biological Sciences where he built a highly functional Biotherapeutics unit serving all therapeutic indications and all research sites within the global Takeda organization. In 2011, he was awarded the venia legendi in pharmacology from the University of Konstanz. He and his team developed a HER-2 specific immunotoxin that subsequently entered the clinic when he studied at the University of Freiburg. After working for several years at various cancer hospitals in Germany and the U.S., he joined the pharmaceutical industry in 1999, where he developed a great passion for drug discovery and development, especially for protein therapeutics.

    He holds an M.S. degree in Biotechnology from the University of Stuttgart (Germany) and a Ph.D. in Tumor Biology (summa cum laude) from the University of Freiburg. He studied cellular biology and pharmacology at the University of Constance.

  • William M. Pardridge, M.D.

    William M. Pardridge, M.D.

    Founder and Chief Scientific Officer

    Dr. Pardridge formed ArmaGen in 2003 and supported the company the first 10 years with $20 million in non-dilutive funding. Dr. Pardridge, who is a Distinguished Professor Emeritus, UCLA, is a recognized leader in blood-brain barrier (BBB) research. He has focused on the area since 1970, and is credited with inventing the antibody directed receptor-mediated transcytosis technology, the liposome technology for non-viral, non-invasive gene therapy of the brain, and the field of BBB genomics. He is the author of over 500 publications, more than 450 of which focus on the BBB. Dr. Pardridge is board certified in Internal Medicine, and Endocrinology and Metabolism.

  • Ruben Boado, Ph.D.

    Ruben Boado, Ph.D.

    Co-founder and Vice President of Research and Development

    Dr. Boado co-founded ArmaGen in 2004, following more than 25 years of academic experience in fields of molecular and cell biology of the BBB, and drug delivery to the brain. His leadership and expertise have been instrumental in the development of ArmaGen’s extensive product pipeline, including potential biotherapeutic treatments for mucopolysaccharidosis, stroke, Alzheimer’s disease and Parkinson’s disease. Dr. Boado was the principal investigator in a number of Small Business Innovation Research (SBIR) programs granted by the National Institutes of Health to ArmaGen. Dr. Boado is also a co-inventor of the intellectual property that supports ArmaGen’s pipeline. He was previously professor of Medicine at UCLA, and has published over 195 scientific peer-reviewed publications and book chapters related to the BBB. Dr. Boado received his Ph.D. in Biochemistry at the University of Buenos Aires.

  • PatriceRioux

    Patrice Rioux, M.D., Ph.D.

    Clinical Consultant

    Dr. Rioux joined ArmaGen in July 2015. His career in clinical drug development spans nearly four decades, during which time he gained extensive experience as a clinician, researcher, medical director and regulatory specialist. His background includes development of drugs and biologic products for various indications across neurodegenerative diseases, immunology, pain management, oncology and metabolic diseases. He was most recently Chief Medical Officer at Raptor Pharmaceuticals, Inc. where he was responsible for securing regulatory approval of a delayed-release cysteamine for the treatment of a lysosomal storage disease, nephropathic cystinosis, in both the U.S. and Europe. He previously served as Chief Medical Officer at Ferrokin Biosciences and Edison Pharmaceuticals, and as Vice President Clinical at Repligen, where he gained significant orphan disease experience in Huntington’s, mitochondrial diseases, autism, Parkinson’s disease and nonalcoholic steatohepatitis (NASH). He has also held senior roles Biogen, Arrow International, Variagenics, Inc., and GRP (Groupement de Recherche en Pharmacologie), and has consulted for Glaxo, SmithKline Beecham, Pfizer, Bristol-Myers Squibb and Lilly. Dr. Rioux received his Medical Education at Faculte de Medecine Pitie-Salpetriere, his Ph.D. in Mathematical Statistics at Faculte des Sciences, and his Degree of Pharmacology (pharmacokinetics and clinical pharmacology) at Faculte de Medecine Pitie-Salpetriere.

  • SheriBarrack

    Sheri Barrack, Ph.D.

    Vice President of Pharmaceutical Development

    Dr. Barrack has more than 25 years of biopharmaceutical industry experience. She has led 10 products from development through commercialization and many investigational compounds from research into clinical development.

    Prior to joining ArmaGen in January of 2016, Dr. Barrack ran a Chemistry, Manufacturing and Controls (CMC) consultancy, sharing her expertise with ArmaGen, Relypsa, Affymax, Cebix, U.S. WorldMeds and others. She was previously Senior Vice President of Pharmaceutical Development at Cebix, Inc.  Prior to Cebix, Dr. Barrack was Vice President of BioPharmaceutical development at Elan Pharmaceutical, where she managed manufacturing, formulation, analytical, clinical trial material distribution, and preparation of the Quality section of regulatory submissions. Before her time at Elan, Dr. Barrack was responsible for chemical, analytical and formulation development at GlycoMed, a role in which she acquired in-depth experience in the different functional areas that encompass pharmaceutical development. Her professional experience also includes roles in process scale-up and manufacturing at Bio-Rad and drug discovery at Monsanto.

    Dr. Barrack received her Ph.D. in Organic Chemistry at the University of California Riverside with focus on the synthesis of Vitamin D analogs.

  • Douglas-Hunt-internet

    Douglas Hunt, FRAPS

    Vice President of Regulatory Affairs and Quality Assurance

    Douglas Hunt has more than 20 years of biopharmaceutical experience, during which he has filed numerous Biologic License Applications (BLAs) and Investigational New Drug (IND) applications. Prior to joining ArmaGen in May 2015, he served as Vice President Global Regulatory Affairs of Baxter Bioscience, a leading manufacturer of recombinant and plasma-based proteins to treat immune deficiencies, hemophilia and other bleeding disorders. Before his tenure at Baxter, Douglas worked at Amgen in various roles of increasing responsibility in both regulatory affairs and manufacturing. Prior to that, he was Senior Director Global Regulatory Affairs at Quintiles. During his tenure at Baxter and Amgen, he led teams that supported global approvals of OBIZUR, RIXUBIS, HYQVIA, PreFLUCEL, NPLATE, ARANESP, ENBREL and NEULASTA. Prior to Quintiles, Mr. Hunt received his B.Sc. in biological sciences from Portsmouth University (UK).

  • Derek Kelaita, M.B.A.

    Derek Kelaita, MBA

    Vice President of Business Development

    Mr. Kelaita has more than 15 years of business/corporate development experience negotiating in-licensing, out-licensing transactions as well as strategic collaborations for public/private biopharmaceutical companies. He has been responsible for licensing/M&A transactions valued at over $1 billion in multiple therapeutic areas including: orphan drugs (ArmaGen), immunotherapy (AnaptysBio), metabolic/diabetes (Cebix), dental (Novalar), infectious disease (Nventa), oncology (Dendreon) and cardiovascular disease (Corvas). Mr. Kelaita brings to ArmaGen a history of successfully directing cross-functional teams of senior executives to achieve business development objectives and provides strategic and tactical advice in the areas of corporate/business development, investor relations, public relations, intellectual property, finance and market research.