Mathias Schmidt, Ph.D.›
Chief Executive Officer
Dr. Schmidt joined ArmaGen as the chief executive officer, as well as member of ArmaGen’s board of directors, in October 2016. Dr. Schmidt has more than 17 years of global biopharmaceutical industry experience in executive management focused on the research and development of biotherapeutics and pharmaceuticals. Prior to ArmaGen, he held various positions with Takeda Pharmaceuticals and its subsidiaries since 2001, including oncology drug discovery, early alliance management and overseeing biologics. He joined Takeda California in 2012 as Vice President of Biological Sciences where he built a highly functional Biotherapeutics unit serving all therapeutic indications and all research sites within the global Takeda organization. In 2011, he was awarded the venia legendi in pharmacology from the University of Konstanz. He and his team developed a HER-2 specific immunotoxin that subsequently entered the clinic when he studied at the University of Freiburg. After working for several years at various cancer hospitals in Germany and the U.S., he joined the pharmaceutical industry in 1999, where he developed a great passion for drug discovery and development, especially for protein therapeutics.
He holds an M.S. degree in Biotechnology from the University of Stuttgart (Germany) and a Ph.D. in Tumor Biology (summa cum laude) from the University of Freiburg. He studied cellular biology and pharmacology at the University of Constance.
William M. Pardridge, M.D.›
Founder and Chief Scientific Officer
Dr. Pardridge formed ArmaGen in 2003 and supported the company the first 10 years with $20 million in non-dilutive funding. Dr. Pardridge, who is a Distinguished Professor Emeritus, UCLA, is a recognized leader in blood-brain barrier (BBB) research. He has focused on the area since 1970, and is credited with inventing the antibody directed receptor-mediated transcytosis technology, the liposome technology for non-viral, non-invasive gene therapy of the brain, and the field of BBB genomics. He is the author of over 500 publications, more than 450 of which focus on the BBB. Dr. Pardridge is board certified in Internal Medicine, and Endocrinology and Metabolism.
Ruben Boado, Ph.D.›
Co-founder and Vice President of Research and Development
Dr. Boado co-founded ArmaGen in 2004, following more than 25 years of academic experience in fields of molecular and cell biology of the BBB, and drug delivery to the brain. His leadership and expertise have been instrumental in the development of ArmaGen’s extensive product pipeline, including potential biotherapeutic treatments for mucopolysaccharidosis, stroke, Alzheimer’s disease and Parkinson’s disease. Dr. Boado was the principal investigator in a number of Small Business Innovation Research (SBIR) programs granted by the National Institutes of Health to ArmaGen. Dr. Boado is also a co-inventor of the intellectual property that supports ArmaGen’s pipeline. He was previously professor of Medicine at UCLA, and has published over 195 scientific peer-reviewed publications and book chapters related to the BBB. Dr. Boado received his Ph.D. in Biochemistry at the University of Buenos Aires.
Joseph G. Phillips, Ph.D.›
Senior Vice President of Pharmaceutical Development
Dr. Joseph Phillips joined ArmaGen in May 2017. In his 27 years of leadership experience in the biopharmaceutical industry he has managed organizations engaged in drug substance and drug product manufacturing process development serving R&D and manufacturing operations.
He led advanced work in genomics, proteomics and metabolomics technologies to understand how cell culture media constituents, bioprocess raw materials and processing conditions impact product quality attributes and productivity to improve prediction of manufacturing results. He pursued the use of high resolution analytical techniques to measure human biological transformation and physiological clearance of drug product variants to assign critical product quality attributes.
Prior to joining ArmaGen, Joseph was a biotechnology consultant to biopharmaceutical executive leaders for bioprocess & product development CMC, manufacturability, QbD, cGMP and technical operations.
Before his consultancy, Joseph held several Executive Director positions at Amgen delivering successful global CMC regulatory submissions for Neulasta, Aranesp, Sensipar/Mimpara, Enbrel, Vectibix, Prolia, XGEVA and Repatha. Prior to Amgen, he served in several leadership roles at GlaxoSmithKline. He started his career in the biopharmaceutical industry at Upjohn (acquired by Pharmacia/Pfizer). Joseph received his Ph.D. in pharmaceutics and analytical chemistry from Brighton University (UK), his M.Sc. in organometallic chemistry from University of Sussex (UK) and his B.Sc. in applied chemistry from Brighton University (UK).